Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395860 | 1.00 | BCAT2 (0.53) | BCAT2CSNK1A1TYRO3DYRK1BNUDT1 | |
| SCHEMBL11509759 | 0.86 | BCAT2 (0.35) | BCAT2CSNK1A1TYRO3DYRK1BNPC1 | |
| SCHEMBL11471190 | 0.85 | RAB9A (0.45) | BCAT2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL31092004 | 0.85 | RAB9A (0.45) | BCAT2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10664169 | 0.83 | KDM4C (0.47) | CSNK1A1TYRO3DYRK1BCHEK1NPC1 | |
| SCHEMBL11357674 | 0.83 | ALDH1A1 (0.39) | BCAT2CSNK1A1TYRO3DYRK1BNPC1 | |
| SCHEMBL21802450 | 0.83 | CTSD (0.44) | ALDH1A1MAPT | |
| SCHEMBL29903396 | 0.81 | PARP1 (0.40) | BCAT2CSNK1A1TYRO3DYRK1BCHEK1 | |
| SCHEMBL10811664 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTATM | |
| SCHEMBL17188156 | 0.80 | CASP1 (0.38) | BCAT2CSNK1A1TYRO3DYRK1BCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1058694-A | Contain 1,2, the Herbicidal combinations of 4-triazole-3-formamide and control method for weed with said composition | KUREHA CHEMICAL IND CO LTD (JP) | 1992-02-19 | — | — | CN | claimed |
| CN-1015455-B | Process for producing 1, 2, 4-triazole-3-carboxamide compound | KUREHA CHEMICAL IND CO LTD (JP) | 1992-02-12 | — | — | CN | claimed |
| CN-86108483-A | 1. 2, 4-triazole-3-carboxamide compound, preparation method thereof and herbicidal composition containing same | — | 1987-09-16 | — | — | CN | claimed |
| EP-4003965-A1 | UREA, AMIDE, AND SUBSTITUTED HETEROARYL COMPOUNDS FOR CBL-B INHIBITION | Nurix Therapeutics, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-105555788-B | Triazol [4,5-d] pyrimidine derivatives | 豪夫迈·罗氏有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-107428740-A | Indazolyl-and indolyl-benzamide derivatives | 埃萨内克斯股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-102595904-B | Novel compositions and methods for preparing 5-amino or substituted amino 1,2, 3-triazoles and triazole orotate formulations | 巧妙疗法股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-104817507-A | Novel compositions and processes for preparing 5-amino or substituted amino 1,2,3-triazoles and triazole orotate formulations | TACTICAL THERAPEUTICS INC | 2015-08-05 | — | — | CN | disclosed |
| CN-102595904-A | Novel compositions and methods for preparing 5-amino or substituted amino 1,2, 3-triazoles and triazole orotate formulations | TACTICAL THERAPEUTICS INC | 2012-07-18 | — | — | CN | disclosed |
| CN-101273988-B | Treatment and prevention of neoplasms with salts of aminoimidazole carboxamide and 5-amino or substituted amino 1,2,3-triazoles | TACTICAL THERAPEUTICS, INC. (US) | 2011-12-14 | — | — | CN | disclosed |
| CN-101273988-A | Treatment and prevention of neoplasms with salts of aminoimidazole carboxamide and 5-amino or substituted amino 1,2,3-triazoles | TACTICAL THERAPEUTICS INC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-1318029-C | Use of salts of aminoimidazole carboxamides and of 5-amino or substituted amino 1,2, 3-triazoles for preparing pharmaceutical compositions for the treatment and prevention of tumors | CONSTANTIA GROUPE CORP (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1191485-A | Treatment and prevention of tumors with salts of aminoimidazole carboxamides and 5-amino or substituted amino 1,2, 3-triazoles | CONSTANTIA GROUPE CORP (AT) | 1998-08-26 | — | — | CN | disclosed |
| CN-1058694-A | Contain 1,2, the Herbicidal combinations of 4-triazole-3-formamide and control method for weed with said composition | KUREHA CHEMICAL IND CO LTD (JP) | 1992-02-19 | — | — | CN | disclosed |
| CN-86108483-A | 1. 2, 4-triazole-3-carboxamide compound, preparation method thereof and herbicidal composition containing same | — | 1987-09-16 | — | — | CN | disclosed |