Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 14/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486928 | 0.88 | NAPRT (0.48) | NFE2L2NAPRTTRIM24TRIM33KDM4E | |
| SCHEMBL8486922 | 0.88 | NAPRT (0.48) | NFE2L2NAPRTTRIM24TRIM33KDM4E | |
| SCHEMBL9000312 | 0.78 | NFE2L2 (0.49) | NFE2L2TRIM24TRIM33KDM4ELMNA | |
| SCHEMBL32661415 | 0.77 | NFE2L2 (0.51) | NFE2L2KDM4E | |
| SCHEMBL31095224 | 0.76 | HSD11B1 (0.43) | NFE2L2NAPRTTRIM24TRIM33KDM4E | |
| SCHEMBL31095207 | 0.76 | HSD11B1 (0.43) | NFE2L2NAPRTTRIM24TRIM33KDM4E | |
| SCHEMBL29576848 | 0.75 | — | — | |
| SCHEMBL172054 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5131556 | 0.74 | TRIM24 (0.55) | NFE2L2NAPRTTRIM24TRIM33KDM4E | |
| SCHEMBL23587022 | 0.73 | NFE2L2 (0.52) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680602-A1 | HETEROCYCLIC COMPOUNDS AS SELECTIVE HDAC6 INHIBITORS | Miralinc Pharma, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192237-A1 | HETEROCYCLIC COMPOUNDS AS SELECTIVE HDAC6 INHIBITORS | MIRALINC PHARMA, INC. (US) | 2024-09-19 | — | — | WO | disclosed |