Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31095224 | 1.00 | HSD11B1 (0.43) | HSD11B1SMN1; SMN2TRIM24TRIM33NAPRT | |
| SCHEMBL8486922 | 0.86 | NAPRT (0.48) | TRIM24TRIM33NAPRTNFE2L2MEN1 | |
| SCHEMBL8486928 | 0.86 | NAPRT (0.48) | TRIM24TRIM33NAPRTNFE2L2MEN1 | |
| SCHEMBL31095221 | 0.83 | NFE2L2 (0.42) | TRIM24TRIM33NAPRTNFE2L2NPC1 | |
| SCHEMBL31095177 | 0.83 | NFE2L2 (0.42) | TRIM24TRIM33NAPRTNFE2L2RELA | |
| SCHEMBL31095230 | 0.82 | NFE2L2 (0.47) | SMN1; SMN2TRIM24TRIM33NAPRTNFE2L2 | |
| SCHEMBL31095227 | 0.77 | CSNK1A1 (0.38) | TRIM24TRIM33NAPRT | |
| SCHEMBL1751871 | 0.77 | HSD11B1 (0.62) | HSD11B1SMN1; SMN2NFE2L2MEN1NPC1 | |
| SCHEMBL297691 | 0.77 | HSD11B1 (0.62) | HSD11B1SMN1; SMN2NFE2L2MEN1NPC1 | |
| SCHEMBL31613215 | 0.77 | HSD11B1 (0.62) | HSD11B1SMN1; SMN2NFE2L2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680602-A1 | HETEROCYCLIC COMPOUNDS AS SELECTIVE HDAC6 INHIBITORS | Miralinc Pharma, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192237-A1 | HETEROCYCLIC COMPOUNDS AS SELECTIVE HDAC6 INHIBITORS | MIRALINC PHARMA, INC. (US) | 2024-09-19 | — | — | WO | disclosed |