Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836209 | 0.79 | ALOX5AP (0.48) | RAB9AKMT2AALOX5APFEN1PTGS2 | |
| SCHEMBL29953072 | 0.77 | MGLL (0.58) | MGLLENPP2KDM4EALDH1A1 | |
| SCHEMBL971732 | 0.76 | MGLL (0.73) | MGLLENPP2KDM4EALDH1A1CA4 | |
| SCHEMBL5734224 | 0.76 | RAB9A (0.64) | RAB9AKMT2AALOX5APFEN1F10 | |
| SCHEMBL13724201 | 0.76 | ALOX5AP (0.48) | RAB9AKMT2AALOX5APFEN1PTGS2 | |
| SCHEMBL937206 | 0.75 | PTGS2 (0.61) | RAB9AKMT2APTGS2KDM4EALDH1A1 | |
| SCHEMBL29415408 | 0.75 | PTGS2 (0.61) | RAB9AKMT2APTGS2KDM4EALDH1A1 | |
| SCHEMBL28797036 | 0.75 | MGLL (0.60) | MGLLENPP2KDM4EALDH1A1CA4 | |
| SCHEMBL5439666 | 0.74 | MGLL (0.70) | MGLLENPP2KDM4EALDH1A1CA4 | |
| SCHEMBL5171111 | 0.74 | BAZ2B (0.50) | RAB9AKMT2ABAZ2BBAZ2ABRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |