Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6096 | 0.89 | ENPP2 (0.61) | MGLLENPP2KDM4EALDH1A1 | |
| SCHEMBL6243674 | 0.84 | KCNH2 (0.50) | KCNH2LOXL2PLK4NR1H2NR1H3 | |
| SCHEMBL2550561 | 0.84 | ENPP2 (0.45) | MGLLENPP2KCNH2LOXL2PLK4 | |
| SCHEMBL12619984 | 0.80 | MGLL (0.86) | MGLLENPP2KDM4EALDH1A1PLG | |
| SCHEMBL30712840 | 0.80 | MGLL (0.86) | MGLLENPP2KDM4EALDH1A1PLG | |
| SCHEMBL31139484 | 0.80 | MGLL (0.86) | MGLLENPP2KDM4EALDH1A1PLG | |
| SCHEMBL2140712 | 0.79 | PTGS2 (0.53) | KCNH2LOXL2ALDH1A1NR1H2NR1H3 | |
| SCHEMBL30855468 | 0.78 | PTGS2 (0.46) | ENPP2KCNH2LOXL2NR1H2NR1H3 | |
| SCHEMBL31095271 | 0.77 | MGLL (0.51) | MGLLENPP2KDM4EALDH1A1 | |
| SCHEMBL14830537 | 0.76 | CA2 (0.68) | MGLLPLGF12F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |