Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPM2A | O95278 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31095644 | 0.86 | CYP2A6 (0.31) | CYP2A6HSP90AA1 | |
| SCHEMBL31095746 | 0.84 | EPM2A (0.40) | EPM2APTPN2PTPN1PTPN22CYP2A6 | |
| SCHEMBL216673 | 0.71 | EPM2A (0.53) | EPM2APTPN2PTPN1PTPN22CYP2A6 | |
| SCHEMBL29432245 | 0.71 | EPM2A (0.53) | EPM2APTPN2PTPN1PTPN22CYP2A6 | |
| SCHEMBL31095709 | 0.70 | EPM2A (0.31) | EPM2APTPN2PTPN1PTPN22CYP2A6 | |
| SCHEMBL28824198 | 0.69 | EPM2A (0.49) | EPM2APTPN2PTPN1PTPN22CYP2A6 | |
| SCHEMBL31095601 | 0.69 | BCKDK (0.43) | EPM2APTPN2PTPN1PTPN22CYP2A6 | |
| SCHEMBL9949673 | 0.68 | CYP2A6 (0.42) | EPM2APTPN2PTPN1PTPN22CYP2A6 | |
| SCHEMBL12811607 | 0.68 | EPM2A (0.50) | EPM2APTPN2PTPN1PTPN22CYP2A6 | |
| SCHEMBL4654001 | 0.67 | PIM1 (0.34) | EPM2APTPN2PTPN1PTPN22CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680247-A1 | DPP1 INHIBITORS WITH POLYCYCLIC LINKERS AND USES THEREOF | Insmed Incorporated (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192416-A1 | DPP1 INHIBITORS WITH POLYCYCLIC LINKERS AND USES THEREOF | INSMED INCORPORATED (US) | 2024-09-19 | — | — | WO | disclosed |