Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | EPM2A | O95278 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 3/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17037081 | 0.91 | EPM2A (0.38) | CYP2A6EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL10227293 | 0.91 | EPM2A (0.44) | CYP2A6EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL17037082 | 0.89 | GPR3 (0.44) | CYP2A6EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL348846 | 0.86 | GPR3 (0.41) | CYP2A6EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL17010965 | 0.86 | CYP2A6 (0.40) | CYP2A6EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL216673 | 0.84 | EPM2A (0.53) | CYP2A6EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL17037089 | 0.83 | BCL2L1 (0.37) | CYP2A6EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL12925791 | 0.80 | HRH4 (0.40) | CYP2A6HRH4HSP90AA1MIFJAK2 | |
| SCHEMBL12811607 | 0.80 | EPM2A (0.50) | CYP2A6EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL10227302 | 0.79 | EPM2A (0.43) | CYP2A6EPM2APTPN2PTPN1PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260451-B2 | Method for producing aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2016-02-16 | — | — | US | disclosed |
| US-9260451-B2 | Method for producing aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20150239901-A1 | Method For Producing Aromatic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150239901-A1 | Method For Producing Aromatic Compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-08-27 | — | — | US | disclosed |
| US-8283660-B2 | Small molecule semiconductor | XEROX CORPORATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283660-B2 | Small molecule semiconductor | XEROX CORPORATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283660-B2 | Small molecule semiconductor | XEROX CORPORATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-20120161109-A1 | SMALL MOLECULE SEMICONDUCTOR | XEROX CORPORATION (US) | 2012-06-28 | — | — | US | disclosed |
| US-20120161109-A1 | SMALL MOLECULE SEMICONDUCTOR | XEROX CORPORATION (US) | 2012-06-28 | — | — | US | disclosed |
| US-20120161109-A1 | SMALL MOLECULE SEMICONDUCTOR | XEROX CORPORATION (US) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239901-A1 | Method For Producing Aromatic Compound | TYR, XDH, CYP1A1 | CYP2A6 125/4885EPM2A 3421/4885PTPN2 3252/4885 |
| US-20120161109-A1 | SMALL MOLECULE SEMICONDUCTOR | SLC43A1, TST, SLC7A5 | CYP2A6 1578/4885EPM2A 1942/4885PTPN2 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.