Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.68 |
| ▸ | CFTR | P13569 | 2/20 | 0.63 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001042 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL30476552 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL30476558 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL477393 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL1242879 | 0.93 | SMN1; SMN2 (0.87) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL10968928 | 0.91 | SMN1; SMN2 (0.82) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL18228789 | 0.89 | SMN1; SMN2 (0.81) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL11605250 | 0.86 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL11062714 | 0.86 | CYP17A1 (0.90) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL2908868 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563786-B2 | Method for producing optically active alcohol | MITSUI CHEMICALS, INC. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-04-12 | — | — | US | disclosed |
| EP-2412694-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | Mitsui Chemicals, Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20080200672-A1 | Highly enantioselective carbonyl reduction with borane catalyzed by chiral spiroborate esters derived from chiral beta-aminoalcohols | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200672-A1 | Highly enantioselective carbonyl reduction with borane catalyzed by chiral spiroborate esters derived from chiral beta-aminoalcohols | ADH1A, ALDH7A1, HSD11B1 | SMN1; SMN2 2228/4885CYP17A1 60/4885CFTR 3922/4885 |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | ADH1A, ADH1C, FHIT | SMN1; SMN2 4362/4885CYP17A1 108/4885CFTR 4850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.