Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.68 |
| ▸ | CFTR | P13569 | 2/20 | 0.63 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.50 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001042 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL30476552 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL30476558 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL477633 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL1242879 | 0.93 | SMN1; SMN2 (0.87) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL10968928 | 0.91 | SMN1; SMN2 (0.82) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL18228789 | 0.89 | SMN1; SMN2 (0.81) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL11605250 | 0.86 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL11062714 | 0.86 | CYP17A1 (0.90) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 | |
| SCHEMBL2908868 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP17A1CFTRGOPCSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104342464-A | Method for producing chiral phenyl methanol employing catalysis of tarlaromyces flavus | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2015-02-11 | — | — | CN | claimed |
| CN-101023064-B | Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors | PFIZER | 2011-02-16 | — | — | CN | claimed |
| CN-101023064-A | Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors | AGOURON PHARMA (US) | 2007-08-22 | — | — | CN | claimed |
| CN-115413657-B | Application of cinnamic acid derivative in mosquito control | 深圳市纬信科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115124528-B | Pyrrolopyridine compound, and preparation method and medical application thereof | 徐州医科大学 | 2023-10-27 | — | — | CN | disclosed |
| US-20230218612-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING INHIBITORY EFFECT ON PRODUCTION OF KYNURENINE | KYOWA KIRIN CO., LTD. (JP) | 2023-07-13 | — | — | US | disclosed |
| CN-115413657-A | Application of cinnamic acid derivative in mosquito control | 五邑大学 | 2022-12-02 | — | — | CN | disclosed |
| EP-3856186-A1 | SMALL MOLECULE INHIBITORS OF DYRK1/CLK AND USES THEREOF | Arizona Board of Regents on behalf of the University of Arizona (US) | 2021-08-04 | — | — | EP | disclosed |
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2021-04-01 | — | — | US | disclosed |
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2021-04-01 | — | — | US | disclosed |
| US-20200179376-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING INHIBITORY EFFECT ON PRODUCTION OF KYNURENINE | KYOWA KIRIN CO., LTD. (JP) | 2020-06-11 | — | — | US | disclosed |
| US-4985447-A | USEFUL FOR TREATMENT AND PREVENTION OF DISEASES DUE TO DYSFUNCTION OF HEART, BRAIN, LUNG AND KIDNEY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |
| US-4851413-A | TREATMENT OF HEART, BRAIN, LUNG OR KIDNEY DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| CN-87100723-A | Quinone derivative, their preparation and use | — | 1987-09-16 | — | — | CN | disclosed |
| EP-0234729-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-02 | — | — | EP | disclosed |
| EP-0148826-A1 | FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1985-07-24 | — | — | EP | disclosed |
| WO-1985000289-A1 | FUNGICIDAL, HERBICIDAL AND PLANT GROWTH REGULATING PYRIDYL-CONTAINING ETHERS | CHEVRON RESEARCH COMPANY (US) | 1985-01-31 | — | — | WO | disclosed |
| US-4407806-A | PRE- AND POSTEMERGENCE HERBICIDES | CHEVRON RESEARCH COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| US-4116665-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179376-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING INHIBITORY EFFECT ON PRODUCTION OF KYNURENINE | KYNU, KMO, IDO1 | SMN1; SMN2 4325/4885CYP17A1 1360/4885CFTR 3434/4885 |
| US-20230218612-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING INHIBITORY EFFECT ON PRODUCTION OF KYNURENINE | KYNU, KMO, IDO1 | SMN1; SMN2 4325/4885CYP17A1 1360/4885CFTR 3434/4885 |
| US-20210093618-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | BRIX1, RDX, SULT2A1 | SMN1; SMN2 2483/4885CYP17A1 950/4885CFTR 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.