SCHEMBL31106922

SCHEMBL31106922

CC(C)(C)[Si](C)(C)OCC1C2CC1(C(=O)O)C2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 1/20 0.32
PPM1D O15297 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30354018 0.85 MAPT (0.30)
SCHEMBL31106937 0.80
SCHEMBL21789031 0.74 TOP2A (0.33) TOP2APPM1D
SCHEMBL30354031 0.73 TOP2A (0.32) TOP2A
SCHEMBL9471481 0.67 TSHR (0.31) TOP2A
SCHEMBL26699681 0.67 FKBP1A (0.33) TOP2APPM1D
SCHEMBL25568329 0.67 PPM1D (0.34) PPM1D
SCHEMBL16875381 0.66 FKBP1A (0.34) TOP2APPM1D
SCHEMBL21789060 0.66 HSD11B1 (0.31) TOP2A
SCHEMBL23883596 0.66 TOP2A (0.33) TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955409-A Cardiac sarcomere inhibitors 赛特凯恩蒂克公司 2024-11-15 CN disclosed
CN-112867539-B Cardiac sarcomere inhibitors 赛特凯恩蒂克公司 2024-08-06 CN disclosed