Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24558170 | 0.84 | DPP4 (0.37) | DPP4DPP8SMN1; SMN2NPC1TP53 | |
| SCHEMBL615255 | 0.73 | NR3C1 (0.33) | KDM4C | |
| SCHEMBL24558265 | 0.72 | CSNK2A2 (0.35) | KDM4CKDM2B | |
| SCHEMBL30417693 | 0.72 | THRB (0.42) | DPP4KDM4CKDM2BRAB9AMAPK1 | |
| SCHEMBL2934931 | 0.69 | DPP4 (0.44) | DPP4DPP8KDM4CSMN1; SMN2NPC1 | |
| SCHEMBL8377346 | 0.68 | DPP4 (0.44) | DPP4KMOSMN1; SMN2TP53MAPK1 | |
| SCHEMBL24463239 | 0.68 | DPP4 (0.37) | DPP4DPP8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30390911 | 0.68 | DPP4 (0.37) | DPP4DPP8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20698152 | 0.67 | DPP4 (0.39) | DPP4DPP8SMN1; SMN2NPC1TP53 | |
| SCHEMBL25939485 | 0.66 | DHODH (0.55) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-B | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2024-07-19 | — | — | CN | disclosed |