Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.37 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31110665 | 0.76 | HTR2B (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL474092 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL474093 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL31110668 | 0.72 | TDP1 (0.36) | ALDH1A1MEN1KMT2ACA12CA7 | |
| SCHEMBL10438847 | 0.69 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL69522 | 0.69 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL31110796 | 0.69 | HTR1A (0.38) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL11061667 | 0.68 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL31110664 | 0.68 | PKM (0.38) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL9255036 | 0.67 | PRKDC (0.42) | ALDH1A1MAPTKDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673141-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024182751-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |