Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087165 | 0.82 | TDP1 (0.40) | L3MBTL1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL1682034 | 0.78 | ALDH1A1 (0.50) | L3MBTL1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL932125 | 0.77 | TDP1 (0.40) | L3MBTL1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL16256389 | 0.77 | GABRA1 (0.48) | L3MBTL1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL10699803 | 0.77 | AR (0.43) | POLBMAPTALDH1A1USP2RECQL | |
| SCHEMBL24673909 | 0.76 | CA12 (0.39) | L3MBTL1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL2536107 | 0.76 | L3MBTL1 (0.43) | L3MBTL1KDM4EPOLBMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL2860880 | 0.76 | ALDH1A1 (0.48) | L3MBTL1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL11295500 | 0.76 | IFNAR1 (0.46) | L3MBTL1KDM4EPOLBMAPTTDP1 | |
| SCHEMBL22535153 | 0.76 | L3MBTL1 (0.43) | L3MBTL1KDM4EPOLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791436-A | 2-Aminopyrimidine derivative and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-10-18 | — | — | CN | disclosed |