Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22535153 | 0.82 | L3MBTL1 (0.43) | TDP1L3MBTL1KDM4EPOLBMAPT | |
| SCHEMBL31112260 | 0.82 | L3MBTL1 (0.43) | TDP1L3MBTL1KDM4EPOLBMAPT | |
| SCHEMBL1135151 | 0.80 | ADRA2B (0.45) | TDP1L3MBTL1KDM4EPOLBMAPT | |
| SCHEMBL12017398 | 0.78 | TAAR1 (0.54) | TDP1L3MBTL1KDM4EPOLBMAPT | |
| SCHEMBL18676085 | 0.78 | ALDH1A1 (0.41) | TDP1L3MBTL1KDM4EPOLBMAPT | |
| SCHEMBL932125 | 0.78 | TDP1 (0.40) | TDP1L3MBTL1KDM4EPOLBMAPT | |
| SCHEMBL14292157 | 0.77 | ATM (0.48) | TDP1L3MBTL1KDM4EPOLBMAPT | |
| SCHEMBL4093561 | 0.77 | CYP3A4 (0.45) | TDP1L3MBTL1KDM4EPOLBMAPT | |
| SCHEMBL30600 | 0.75 | TDP1 (0.55) | TDP1ALDH1A1TAAR1IDO1 | |
| SCHEMBL17750799 | 0.75 | KDM4E (0.38) | TDP1L3MBTL1KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679254-A | The piperidines ketone that is used for inflammation treatment | BIOLIPOX AB | 2010-03-24 | — | — | CN | disclosed |
| US-4460597-A | Herbicidal 5-aminoalkoxy-4-benzoyl-1,3-dimethyl-pyrazole derivatives | SANKYO COMPANY, LIMITED (JP) | 1984-07-17 | — | — | US | disclosed |