SCHEMBL311167

SCHEMBL311167

c1ccc(-c2ccccc2-c2cc3c4cc(-c5ccccc5-c5ccccc5)c(-c5ccccc5-c5ccccc5)cc4c4cc(-c5ccccc5-c5ccccc5)c(-c5ccccc5-c5ccccc5)cc4c3cc2-c2ccccc2-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.48
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
APAF1 O14727 1/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
XBP1 P17861 1/20 0.46
PTBP1 P26599 1/20 0.46
RAB9A P51151 1/20 0.46
GALK1 P51570 1/20 0.46
BLM P54132 1/20 0.46
SMAD3 P84022 1/20 0.46
ATM Q13315 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 6/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825024 0.88 BACE1 (0.52) BACE1MEN1MAPTKMT2AHTT
SCHEMBL31438454 0.85 BACE1 (0.55) BACE1MEN1MAPTKMT2AHTT
SCHEMBL311836 0.85 BACE1 (0.55) BACE1MEN1MAPTKMT2AHTT
SCHEMBL30332559 0.85 ALDH1A1 (0.58) BACE1MEN1MAPTKMT2AHTT
SCHEMBL29414275 0.85 ALDH1A1 (0.58) BACE1MEN1MAPTKMT2AHTT
SCHEMBL29414264 0.85 ALDH1A1 (0.58) BACE1MEN1MAPTKMT2AHTT
SCHEMBL192419 0.85 ALDH1A1 (0.58) BACE1MEN1MAPTKMT2AHTT
SCHEMBL608537 0.85 ALDH1A1 (0.58) BACE1MEN1MAPTKMT2AHTT
SCHEMBL29352295 0.85 ALDH1A1 (0.58) BACE1MEN1MAPTKMT2AHTT
SCHEMBL29355309 0.82 ALDH1A1 (0.55) BACE1MEN1MAPTKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 US disclosed
US-10957858-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-23 US disclosed
US-20190245147-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-08 US disclosed
US-10312450-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-06-04 US disclosed
EP-3424918-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2019-01-09 EP disclosed
EP-3064563-B1 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2018-12-26 EP disclosed
EP-3112336-B1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2018-08-01 EP disclosed
US-20170179394-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2017-06-22 US disclosed
US-20130001538-A1 Triphenylene Hosts in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-01-03 US disclosed
EP-1888708-B1 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2012-11-21 EP disclosed
EP-2511254-A2 Single triphenylene chromophores in phosphorescent light emitting diodes Universal Display Corporation (US) 2012-10-17 EP disclosed
US-20120032156-A1 Triphenylene Hosts in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION 2012-02-09 US disclosed
US-8092924-B2 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-01-10 US disclosed
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2011-04-14 US disclosed
EP-2277978-A2 Triphenylene hosts in phosphorescent light emitting diodes Universal Display Corporation (US) 2011-01-26 EP disclosed
EP-1888708-A2 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2008-02-20 EP disclosed
US-20060280965-A1 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION 2006-12-14 US disclosed
WO-2006130598-A2 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2006-12-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179394-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 BACE1 2779/4885MEN1 382/4885MAPT 3291/4885
US-10312450-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 BACE1 2779/4885MEN1 382/4885MAPT 3291/4885
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES TYR, PNP, MAPRE2 BACE1 4439/4885MEN1 3427/4885MAPT 286/4885
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, TYR BACE1 3004/4885MEN1 641/4885MAPT 3312/4885
US-10957858-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 BACE1 2779/4885MEN1 382/4885MAPT 3291/4885
US-11690286-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 BACE1 2779/4885MEN1 382/4885MAPT 3291/4885
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 BACE1 2779/4885MEN1 382/4885MAPT 3291/4885
US-20190245147-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 BACE1 2779/4885MEN1 382/4885MAPT 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.