SCHEMBL31120406

SCHEMBL31120406

C=CS(=O)(=O)Oc1ccc2c(C)cc(=O)oc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.71
KDM4E B2RXH2 8/20 0.71
GAA P10253 5/20 0.71
STS P08842 2/20 0.69
CA2 P00918 2/20 0.69
HSD17B10 Q99714 5/20 0.61
HPGD P15428 4/20 0.61
ALPL P05186 3/20 0.59
ALPI P09923 3/20 0.59
GLA P06280 4/20 0.56
KMT2A Q03164 3/20 0.53
TP53 P04637 1/20 0.53
MAPT P10636 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
ALDH2 P05091 2/20 0.52
TSHR P16473 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAOA P21397 3/20 0.51
MAOB P27338 3/20 0.51
NPC1 O15118 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10850187 0.83 KDM4E (1.00) ALDH1A1KDM4EGAASTSCA2
SCHEMBL30139608 0.82 ALDH1A1 (0.76) ALDH1A1KDM4EGAASTSCA2
SCHEMBL38662608 0.82 ALDH1A1 (0.76) ALDH1A1KDM4EGAASTSCA2
SCHEMBL25184 0.82 ALDH1A1 (0.76) ALDH1A1KDM4EGAASTSCA2
SCHEMBL9451464 0.82 STS (1.00) ALDH1A1KDM4EGAASTSCA2
Potassium Ion SCHEMBL380405 0.81 KDM4E (0.74) ALDH1A1KDM4EGAASTSCA2
SCHEMBL3761326 0.81 ALDH1A1 (0.74) ALDH1A1KDM4EGAASTSCA2
SCHEMBL3761324 0.81 KDM4E (0.74) ALDH1A1KDM4EGAASTSCA2
SCHEMBL1358798 0.80 KDM4E (0.72) ALDH1A1KDM4EGAASTSCA2
SCHEMBL10850733 0.77 MAOB (0.70) ALDH1A1KDM4EGAASTSCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724857-A Biochemical reagent for detecting mercapto of biological medicine and preparation method thereof 中国医学科学院药物研究所 2024-10-01 CN disclosed