Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.70 |
| ▸ | ADAMTS5 | Q9UNA0 | 18/20 | 0.66 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.57 |
| ▸ | MMP2 | P08253 | 3/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23745358 | 0.88 | ADAMTS4 (0.67) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL23745396 | 0.85 | ADAMTS5 (0.72) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL23745296 | 0.85 | ADAMTS5 (0.68) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL23745361 | 0.85 | ADAMTS5 (0.69) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL19691587 | 0.83 | ADAMTS4 (1.00) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL23745279 | 0.83 | ADAMTS4 (0.63) | ADAMTS4ADAMTS5MMP2MMP13ADAMTS1 | |
| SCHEMBL23727481 | 0.82 | ADAMTS5 (0.58) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL23727483 | 0.82 | ADAMTS5 (0.58) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL29262510 | 0.81 | ADAMTS5 (0.66) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 | |
| SCHEMBL22892283 | 0.79 | ADAMTS4 (0.77) | ADAMTS4ADAMTS5ADAM17MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299360-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD (CN) | 2024-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299360-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | ADAMTS5, ADAMTS4, ADAMTS1 | ADAMTS4 2/4885ADAMTS5 1/4885ADAM17 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.