Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 14/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123807 | 0.85 | NNMT (0.36) | NNMTPRMT5WDR77ACACB | |
| SCHEMBL31123723 | 0.82 | NNMT (0.34) | NNMTPRMT5WDR77ACACBSLC29A1 | |
| SCHEMBL21682082 | 0.82 | NNMT (0.34) | NNMTPRMT5WDR77ACACBSLC29A1 | |
| SCHEMBL10248595 | 0.81 | NNMT (0.41) | NNMTPRMT5WDR77 | |
| SCHEMBL31123774 | 0.79 | PRMT5 (0.33) | NNMTPRMT5WDR77ACACBSLC29A1 | |
| SCHEMBL31123757 | 0.79 | PRMT5 (0.33) | NNMTPRMT5WDR77ACACBSLC29A1 | |
| SCHEMBL18925736 | 0.78 | ACACB (0.41) | NNMTPRMT5WDR77ACACBSLC29A1 | |
| SCHEMBL9469927 | 0.77 | NNMT (0.42) | NNMTPRMT5WDR77 | |
| SCHEMBL9109736 | 0.76 | AHCY (0.52) | NNMTPRMT5WDR77 | |
| SCHEMBL22002025 | 0.76 | AHCY (0.52) | NNMTPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |