Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | NNMT | P40261 | 14/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22002025 | 1.00 | AHCY (0.52) | AHCYADORA2BNNMTPRMT5WDR77 | |
| SCHEMBL18572585 | 1.00 | AHCY (0.52) | AHCYADORA2BNNMTPRMT5WDR77 | |
| SCHEMBL29540101 | 0.89 | NNMT (0.43) | AHCYADORA2BNNMTPRMT5WDR77 | |
| SCHEMBL22509889 | 0.89 | NNMT (0.43) | AHCYADORA2BNNMTPRMT5WDR77 | |
| SCHEMBL9469927 | 0.86 | NNMT (0.42) | NNMTPRMT5WDR77 | |
| SCHEMBL24465141 | 0.85 | PRMT5 (0.67) | AHCYADORA2BPRMT5WDR77 | |
| SCHEMBL18571689 | 0.85 | PRMT5 (0.67) | AHCYADORA2BPRMT5WDR77 | |
| SCHEMBL29325375 | 0.85 | PRMT5 (0.67) | AHCYADORA2BPRMT5WDR77 | |
| SCHEMBL10186262 | 0.85 | AHCY (0.52) | AHCYADORA2BPRMT5WDR77 | |
| SCHEMBL29323387 | 0.85 | PRMT5 (0.67) | AHCYADORA2BPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704854-A2 | PRMT INHIBITOR COMPOUNDS AND THE USES THEREOF | Purdue Research Foundation (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20250332238-A1 | INHIBITION OF HISTONE METHYL TRANSFERASES TO TREAT CANCER | ALBERT-LUDWIGS-UNIVERSITAT FREIBURG (DE) | 2025-10-30 | — | — | US | disclosed |
| US-12357680-B2 | Inhibition of histone methyl transferases to treat cancer | ALBERT-LUDWIGS-UNIVERSITAT FREIBURG (DE) | 2025-07-15 | — | — | US | disclosed |
| US-20250188110-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2025-06-12 | — | — | US | disclosed |
| US-20250017936-A1 | CELL-POTENT BISUBSTRATE INHIBITORS FOR NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2025-01-16 | — | — | US | disclosed |
| US-12173026-B2 | PRMT5 inhibitors | MERCK SHARP & DOHME LLC (US) | 2024-12-24 | — | — | US | disclosed |
| WO-2024229435-A2 | PRMT INHIBITOR COMPOUNDS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2024-11-07 | — | — | WO | disclosed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-112805006-B | PRMT5 inhibitors | 默沙东有限责任公司 | 2024-09-24 | — | — | CN | disclosed |
| US-20140051654-A1 | Substituted Purine and 7-Deazapurine Compounds | Epizyme, Inc. (US) | 2014-02-20 | — | — | US | disclosed |
| US-20130338173-A1 | Carbocycle-Substituted Purine And 7-Deazapurine Compounds | Epizyme, Inc. (US) | 2013-12-19 | — | — | US | disclosed |
| US-8580762-B2 | Substituted purine and 7-deazapurine compounds | Epizyme, Inc. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580762-B2 | Substituted purine and 7-deazapurine compounds | Epizyme, Inc. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580762-B2 | Substituted purine and 7-deazapurine compounds | Epizyme, Inc. (US) | 2013-11-12 | — | — | US | disclosed |
| WO-2012075492-A2 | CARBOCYCLE-SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS | Epizyme, Inc. (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012075381-A1 | SUBSTITUTED PURINE AND 7 - DEAZAPURINE COMPOUNDS AS MODULATORS OF EPIGENETIC ENZYMES | Epizyme, Inc. (US) | 2012-06-07 | — | — | WO | disclosed |
| US-20120142625-A1 | Substituted Purine And 7-Deazapurine Compounds | Epizyme, Inc. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142625-A1 | Substituted Purine And 7-Deazapurine Compounds | Epizyme, Inc. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142625-A1 | Substituted Purine And 7-Deazapurine Compounds | Epizyme, Inc. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250017936-A1 | CELL-POTENT BISUBSTRATE INHIBITORS FOR NICOTINAMIDE N-METHYLTRANSFERASE (NNMT) AND USES THEREOF | NNMT, NAMPT, NNT | AHCY 88/4885ADORA2B 4126/4885NNMT 1/4885 |
| US-20250188110-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | KMT5A, KMT5B, KMT5C | AHCY 1576/4885ADORA2B 2803/4885NNMT 99/4885 |
| US-20250332238-A1 | INHIBITION OF HISTONE METHYL TRANSFERASES TO TREAT CANCER | KMT2A, KMT5A, DOT1L | AHCY 142/4885ADORA2B 4016/4885NNMT 107/4885 |
| US-12173026-B2 | PRMT5 inhibitors | PRMT5, PRMT1, PRMT3 | AHCY 378/4885ADORA2B 2524/4885NNMT 735/4885 |
| US-12357680-B2 | Inhibition of histone methyl transferases to treat cancer | KMT2A, KMT5A, DOT1L | AHCY 142/4885ADORA2B 4016/4885NNMT 107/4885 |
| US-20130338173-A1 | Carbocycle-Substituted Purine And 7-Deazapurine Compounds | TPMT, MECP2, DAZAP1 | AHCY 69/4885ADORA2B 584/4885NNMT 74/4885 |
| US-20140051654-A1 | Substituted Purine and 7-Deazapurine Compounds | TPMT, DIMT1, DAZAP1 | AHCY 117/4885ADORA2B 651/4885NNMT 68/4885 |
| US-20120142625-A1 | Substituted Purine And 7-Deazapurine Compounds | TPMT, DIMT1, DAZAP1 | AHCY 117/4885ADORA2B 651/4885NNMT 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.