SCHEMBL3112641

SCHEMBL3112641

CC(C)(C)OC(=O)N1CCN(c2ccc(COCCF)cc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 1/20 0.55
▸ CRBN Q96SW2 1/20 0.55
▸ LMNA P02545 3/20 0.55
▸ MAPT P10636 3/20 0.55
▸ ALDH1A1 P00352 1/20 0.55
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ CYP2C19 P33261 1/20 0.54
▸ HTT P42858 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53
▸ GPR119 Q8TDV5 9/20 0.53
▸ NAMPT P43490 1/20 0.48
▸ KIT P10721 1/20 0.47
▸ FLT3 P36888 1/20 0.47
▸ ESRRB O95718 1/20 0.46
▸ ESR1 P03372 1/20 0.46
▸ ESRRA P11474 1/20 0.46
▸ ESRRG P62508 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8858016 0.84 MAPT (0.61) DDB1CRBNLMNAMAPTALDH1A1
SCHEMBL3114683 0.83 MAPT (0.57) DDB1CRBNLMNAMAPTALDH1A1
SCHEMBL3116747 0.83 MAPT (0.57) DDB1CRBNLMNAMAPTALDH1A1
SCHEMBL1019005 0.82 MAPT (0.62) DDB1CRBNLMNAMAPTALDH1A1
SCHEMBL3122680 0.82 GRM5 (0.53) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL5573222 0.82 MAPT (0.76) LMNAMAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL23355487 0.81 MAPT (0.61) DDB1CRBNLMNAMAPTALDH1A1
SCHEMBL22638159 0.81 KIT (0.65) DDB1CRBNLMNAMAPTALDH1A1
SCHEMBL1136833 0.81 MAPT (0.64) DDB1CRBNLMNAMAPTALDH1A1
SCHEMBL3807661 0.81 MAPT (0.64) DDB1CRBNLMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12324845-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2025-06-10 — — US disclosed
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-22 — — US disclosed
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2022-09-15 — — US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 — — US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 — — US disclosed
EP-2474525-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-15 — — EP disclosed
EP-2474523-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-08 — — EP disclosed
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2018-11-29 — — US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 — — US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 — — US disclosed
EP-2474524-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474523-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474525-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474526-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
EP-2114873-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION Lantheus Medical Imaging, Inc. (US) 2009-11-11 — — EP disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 — — WO disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10010631-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 DDB1 3168/4885CRBN 1238/4885LMNA 1041/4885
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 DDB1 3168/4885CRBN 1238/4885LMNA 1041/4885
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 DDB1 3168/4885CRBN 1238/4885LMNA 1041/4885
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 DDB1 3168/4885CRBN 1238/4885LMNA 1041/4885
US-11241509-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 DDB1 3255/4885CRBN 1497/4885LMNA 1194/4885
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 DDB1 3168/4885CRBN 1238/4885LMNA 1041/4885
US-12324845-B2 Ligands for imaging cardiac innervation CHRNB4, RXFP4, RXFP3 DDB1 3066/4885CRBN 372/4885LMNA 3406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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