Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | PDE6C | P51160 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29344733 | 0.89 | ALDH1A1 (0.36) | ALDH1A1HTTKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL29344718 | 0.87 | DHFR (0.37) | ALDH1A1ABCB11HTTKDM4EL3MBTL1 | |
| SCHEMBL29344742 | 0.85 | HSP90AA1 (0.33) | KDM4EHSP90AA1HSP90AB1 | |
| SCHEMBL23327500 | 0.81 | ALDH1A1 (0.43) | ALDH1A1PDE1BHTTKDM4ENPSR1 | |
| SCHEMBL26098304 | 0.81 | PTPN1 (0.49) | ALDH1A1HTTKDM4ENPSR1TDP1 | |
| SCHEMBL23351205 | 0.79 | ALDH1A1 (0.35) | ALDH1A1PDE1BHTTKDM4ENPSR1 | |
| SCHEMBL23327454 | 0.77 | MAPT (0.42) | ALDH1A1PDE1BPOLBPTPN1CCNT1 | |
| SCHEMBL23327537 | 0.77 | NR3C2 (0.38) | ALDH1A1HTTKDM4ENPSR1TDP1 | |
| SCHEMBL21811192 | 0.77 | KDM4E (0.44) | ALDH1A1HTTKDM4ENPSR1TDP1 | |
| SCHEMBL23327703 | 0.76 | KDM4E (0.36) | ALDH1A1HTTKDM4ENPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151992-A1 | PREPARATION OF A TYK2 INHIBITOR | VENTYX BIOSCIENCES, INC. (US) | 2024-07-18 | — | — | WO | disclosed |