SCHEMBL31126901

SCHEMBL31126901

Cc1c(C=O)sc2c(F)cc(F)cc12

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.34
CYP17A1 P05093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12095309 0.76 ERN1 (0.34) ERN1
SCHEMBL1251780 0.76 CYP17A1 (0.49) CYP17A1
SCHEMBL31126974 0.73
SCHEMBL12095255 0.72 BCKDK (0.41) CYP17A1
SCHEMBL31126998 0.71
SCHEMBL2892908 0.71 GPR35 (0.46)
SCHEMBL16934966 0.70 KDM4E (0.31)
SCHEMBL31126894 0.69 DHODH (0.32)
SCHEMBL31126960 0.66 ALDH1A1 (0.45)
SCHEMBL12680460 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024199430-A1 PI3Kα INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF 长春金赛药业有限责任公司 2024-10-03 WO disclosed