Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107522 | 0.95 | AKR1C1 (0.76) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL2440267 | 0.93 | AKR1C1 (0.73) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL3116138 | 0.91 | AKR1C1 (0.61) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL1667343 | 0.86 | AKR1C1 (0.91) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL8105149 | 0.84 | AKR1C1 (0.88) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL11665752 | 0.84 | AKR1C1 (0.88) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL2184245 | 0.83 | AKR1C1 (0.64) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL248544 | 0.83 | AKR1C1 (0.64) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL12928712 | 0.83 | AKR1C1 (0.64) | AKR1C1HDAC4MEN1KMT2AHSD11B1 | |
| SCHEMBL65167 | 0.82 | AKR1C1 (1.00) | AKR1C1HDAC4MEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179343-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-07-15 | — | — | US | claimed |
| WO-2008121074-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-10-09 | — | — | WO | claimed |
| CN-112759587-A | 3- (dimethylamino methyl) piperidine-4-alcohol derivative and preparation method and pharmaceutical application thereof | 复旦大学 | 2021-05-07 | — | — | CN | disclosed |
| CN-105431432-B | Quinine class compound, its optical isomer and preparation method thereof and medical usage | 北京硕佰医药科技有限责任公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-105431432-A | Quinine compounds, and optical isomers, preparation method and medical use thereof | BEIJING JIASHI LIANBO PHARM SCI & TECH CO LTD | 2016-03-23 | — | — | CN | disclosed |
| US-20100179343-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-07-15 | — | — | US | disclosed |
| US-7732544-B2 | Titanium compound and process for producing optically active cyanohydrins | MITSUI CHEMICALS, INC. (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-1806336-B1 | TITANIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRINS | MITSUI CHEMICALS INC (JP) | 2009-09-30 | — | — | EP | disclosed |
| WO-2008121074-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-10-09 | — | — | WO | disclosed |
| US-20070265463-A1 | Titanium Compound and Process for Producing Optically Active Cyanohydrins | MITSUI CHEMICALS, INC. (JP) | 2007-11-15 | — | — | US | disclosed |
| EP-1806336-A1 | TITANIUM COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRINS | Mitsui Chemicals, Inc. (JP) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179343-A1 | METHOD OF PRODUCING AN OPTICALLY ACTIVE CYANOHYDRIN DERIVATIVE | TDO2, AOX1, DAO | AKR1C1 766/4885HDAC4 1548/4885MEN1 4177/4885 |
| US-20070265463-A1 | Titanium Compound and Process for Producing Optically Active Cyanohydrins | WNT1, C3AR1, TDO2 | AKR1C1 1102/4885HDAC4 3930/4885MEN1 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.