Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 3/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21818641 | 1.00 | KDM4E (0.38) | KDM4EASPHKDM8KDM4CKDM5A | |
| SCHEMBL827640 | 0.76 | SPR (0.43) | KDM4EASPHKDM8KDM4CKDM5A | |
| SCHEMBL27138365 | 0.73 | KDM4E (0.40) | KDM4EASPHKDM8KDM4CKDM5A | |
| SCHEMBL20897927 | 0.73 | WNT3A (0.33) | TNKSWNT3ATNKS2 | |
| SCHEMBL25527883 | 0.73 | WNT3A (0.33) | TNKSWNT3ATNKS2 | |
| SCHEMBL31133463 | 0.73 | WNT3A (0.33) | TNKSWNT3ATNKS2 | |
| SCHEMBL21818680 | 0.70 | PARP1 (0.40) | KDM4EFABP4FABP5ALDH1A1ALOX15 | |
| SCHEMBL31133375 | 0.70 | HSD11B1 (0.36) | KDM4EMAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL21818659 | 0.70 | HSD11B1 (0.36) | KDM4EMAPTTSHRLMNASMN1; SMN2 | |
| SCHEMBL24656368 | 0.69 | WNT3A (0.32) | TNKSWNT3ATNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164459-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-03 | — | — | CN | disclosed |