Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26818254 | 0.87 | WNT3A (0.36) | WNT3ATNKS2 | |
| SCHEMBL25527883 | 0.77 | WNT3A (0.33) | WNT3ATNKS2TNKS | |
| SCHEMBL22387691 | 0.75 | NOS3 (0.36) | — | |
| SCHEMBL22019768 | 0.75 | GRM4 (0.36) | — | |
| SCHEMBL20897927 | 0.74 | WNT3A (0.33) | WNT3ATNKS2TNKS | |
| SCHEMBL31133463 | 0.74 | WNT3A (0.33) | WNT3ATNKS2TNKS | |
| SCHEMBL14289084 | 0.72 | — | — | |
| SCHEMBL21818659 | 0.71 | HSD11B1 (0.36) | WNT3ATNKS2TNKS | |
| SCHEMBL31133375 | 0.71 | HSD11B1 (0.36) | WNT3ATNKS2TNKS | |
| SCHEMBL12395081 | 0.70 | ATM (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | WNT3A 3874/4885TNKS2 3411/4885TNKS 3262/4885 |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | WNT3A 3874/4885TNKS2 3411/4885TNKS 3262/4885 |
| US-11820766-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | WNT3A 3874/4885TNKS2 3411/4885TNKS 3262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.