Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31133451 | 0.76 | CHEK1 (0.32) | — | |
| SCHEMBL31133391 | 0.76 | CYP1A2 (0.47) | CSNK2A1 | |
| SCHEMBL31133515 | 0.74 | TTK (0.36) | TTKMAPK8 | |
| SCHEMBL31133579 | 0.74 | TTK (0.36) | TTKMAPK8 | |
| SCHEMBL30301459 | 0.73 | IDO1 (0.33) | — | |
| SCHEMBL25419245 | 0.72 | TRPA1 (0.52) | — | |
| SCHEMBL31472533 | 0.72 | TRPA1 (0.52) | — | |
| SCHEMBL29953501 | 0.72 | TTK (0.62) | TTK | |
| SCHEMBL4514654 | 0.72 | TTK (0.48) | TTK | |
| SCHEMBL586488 | 0.72 | TTK (0.62) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688750-A1 | SUBSTITUTED INDAZOLE PROPIONIC ACID DERIVATIVE COMPOUNDS AND USES THEREOF AS AMPK ACTIVATORS | Pfizer Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024209363-A1 | SUBSTITUTED INDAZOLE PROPIONIC ACID DERIVATIVE COMPOUNDS AND USES THEREOF AS AMPK ACTIVATORS | PFIZER INC. (US) | 2024-10-10 | — | — | WO | disclosed |
| US-20240336572-A1 | SUBSTITUTED INDAZOLE PROPIONIC ACID DERIVATIVE COMPOUNDS AND USES THEREOF | PFIZER INC. (US) | 2024-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336572-A1 | SUBSTITUTED INDAZOLE PROPIONIC ACID DERIVATIVE COMPOUNDS AND USES THEREOF | PRKAG3, PRKAG1, PRKAG2 | TTK 211/4885CSNK2A1 536/4885MAPK8 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.