Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118211 | 0.84 | MAPT (0.41) | MAPTHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL3114641 | 0.83 | XDH (0.46) | MAPTHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL3113702 | 0.83 | GFER (0.41) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4234097 | 0.83 | GFER (0.41) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3119585 | 0.72 | GFER (0.39) | MEN1KMT2AALDH1A1HDAC6 | |
| SCHEMBL4236498 | 0.72 | GFER (0.39) | MEN1KMT2AALDH1A1HDAC6 | |
| SCHEMBL3119429 | 0.71 | GFER (0.37) | MAPTALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL3119435 | 0.71 | GFER (0.37) | MAPTALDH1A1HDAC2HDAC8HDAC6 | |
| SCHEMBL3121578 | 0.69 | MMP2 (0.36) | MAPTMEN1KMT2AALDH1A1HDAC6 | |
| SCHEMBL3121585 | 0.69 | MMP2 (0.36) | MAPTMEN1KMT2AALDH1A1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971581-B1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-04-07 | — | — | EP | disclosed |