Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696302 | 0.92 | LIG1 (0.71) | LIG1CYP3A4KDM4EADRB2ADRB1 | |
| SCHEMBL132849 | 0.83 | LIG1 (0.63) | LIG1CYP3A4KDM4EADRB2ADRB1 | |
| 1-Hydroxy-2-Allyloxybenzene SCHEMBL1562951 | 0.81 | GAA (0.59) | LIG1CYP3A4KDM4EADRB2ADRB1 | |
| SCHEMBL29519569 | 0.80 | LIG1 (0.69) | LIG1CYP3A4KDM4EADRB2ADRB1 | |
| SCHEMBL40310 | 0.80 | LIG1 (0.69) | LIG1CYP3A4KDM4EADRB2ADRB1 | |
| SCHEMBL3996860 | 0.79 | STS (0.55) | LIG1CYP3A4KDM4EHPGDHSD17B10 | |
| SCHEMBL22215906 | 0.79 | LIG1 (0.58) | LIG1CYP3A4KDM4EADRB2ADRB1 | |
| SCHEMBL6656828 | 0.79 | LIG1 (0.58) | LIG1CYP3A4KDM4EADRB2ADRB1 | |
| SCHEMBL3798396 | 0.79 | KDM4E (0.71) | LIG1CYP3A4KDM4EADRB2ADRB1 | |
| SCHEMBL1889645 | 0.79 | LIG1 (0.67) | LIG1CYP3A4KDM4EADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046883-B1 | IMPROVED PROCESSING CONDITIONS OF POLYETHYLENE ARTICLES IN COURSE OF THEIR MANUFACTURE BY MELT PROCESSING | CLARIANT FINANCE BVI LTD (VG) | 2009-12-09 | — | — | EP | disclosed |
| US-20090186987-A1 | Processing Conditions Of Polyethylene Articles In Course Of Their Manufacture By Melt Processing | CLARIANT FINANCE (BVI) LIMITED (VG) | 2009-07-23 | — | — | US | disclosed |
| US-20090186987-A1 | Processing Conditions Of Polyethylene Articles In Course Of Their Manufacture By Melt Processing | CLARIANT FINANCE (BVI) LIMITED (VG) | 2009-07-23 | — | — | US | disclosed |
| US-20090186987-A1 | Processing Conditions Of Polyethylene Articles In Course Of Their Manufacture By Melt Processing | CLARIANT FINANCE (BVI) LIMITED (VG) | 2009-07-23 | — | — | US | disclosed |
| EP-2046883-A1 | IMPROVED PROCESSING CONDITIONS OF POLYETHYLENE ARTICLES IN COURSE OF THEIR MANUFACTURE BY MELT PROCESSING | Clariant International Ltd. (CH) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012319-A1 | IMPROVED PROCESSING CONDITIONS OF POLYETHYLENE ARTICLES IN COURSE OF THEIR MANUFACTURE BY MELT PROCESSING | CLARIANT INTERNATIONAL LTD (CH) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008012319-A1 | IMPROVED PROCESSING CONDITIONS OF POLYETHYLENE ARTICLES IN COURSE OF THEIR MANUFACTURE BY MELT PROCESSING | CLARIANT INTERNATIONAL LTD (CH) | 2008-01-31 | — | — | WO | disclosed |
| US-7074853-B2 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION (US) | 2006-07-11 | — | — | US | disclosed |
| US-6861458-B2 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION (US) | 2005-03-01 | — | — | US | disclosed |
| US-20050014951-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2005-01-20 | — | — | US | disclosed |
| US-6803395-B2 | POLYSILOXANE HAVING THEREON A HYDROPHILIC MOIETY AND A LIGHTFASTNESS MOIETY | XEROX CORPORATION | 2004-10-12 | — | — | US | disclosed |
| US-20030137570-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2003-07-24 | — | — | US | disclosed |
| US-20030133886-A1 | Photoprotective and lightfastness-enhancing siloxanes | XEROX CORPORATION | 2003-07-17 | — | — | US | disclosed |
| US-6569511-B1 | Polysiloxane having a hydrophilic moiety and a lightfastness moiety; ink jet coating | XEROX CORPORATION | 2003-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014951-A1 | Photoprotective and lightfastness-enhancing siloxanes | LRRFIP1, LRRC59, MMS19 | LIG1 66/4885CYP3A4 2957/4885KDM4E 1625/4885 |
| US-20030133886-A1 | Photoprotective and lightfastness-enhancing siloxanes | ITGA1, ITGB1, ITGB8 | LIG1 245/4885CYP3A4 2434/4885KDM4E 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.