Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 15/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31138403 | 0.85 | USP1 (0.42) | USP1 | |
| SCHEMBL30462049 | 0.84 | PTGS2 (0.37) | USP1PTGS2PTGS1CDK2GSK3B | |
| SCHEMBL31537629 | 0.81 | USP1 (0.40) | USP1PTGS2PTGS1 | |
| SCHEMBL31155904 | 0.80 | CCR1 (0.38) | USP1PTGS2PTGS1 | |
| SCHEMBL31138559 | 0.78 | HDAC1 (0.33) | USP1 | |
| SCHEMBL31155941 | 0.77 | USP1 (0.44) | USP1PTGS2PTGS1 | |
| SCHEMBL31155901 | 0.76 | USP1 (0.45) | USP1PTGS2PTGS1 | |
| SCHEMBL31255086 | 0.76 | USP1 (0.42) | USP1PTGS2PTGS1 | |
| SCHEMBL31155925 | 0.75 | PDCD1 (0.46) | USP1PTGS2PTGS1 | |
| SCHEMBL26627762 | 0.75 | USP1 (0.48) | USP1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024208292-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITOR, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2024-10-10 | — | — | WO | disclosed |