6-Hydroxyflavone

6-Hydroxyflavone

SCHEMBL676594

O=c1cc(-c2ccccc2)oc2ccc(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
NPC1 O15118 5/20 1.00
RAB9A P51151 5/20 1.00
CALM1 P0DP23 2/20 1.00
PKM P14618 2/20 1.00
FTO Q9C0B1 2/20 1.00
TP53 P04637 6/20 0.82
SMN1; SMN2 Q16637 5/20 0.82
HPGD P15428 5/20 0.82
CYP3A4 P08684 5/20 0.82
ALOX15 P16050 2/20 0.82
LMNA P02545 1/20 0.82
THRB P10828 1/20 0.82
CASP3 P42574 1/20 0.82
SENP8 Q96LD8 1/20 0.82
SENP7 Q9BQF6 1/20 0.82
SENP6 Q9GZR1 1/20 0.82
IP6K2 Q9UHH9 1/20 0.82
ALDH1A1 P00352 2/20 0.80
GLA P06280 1/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Hydroxyflavone SCHEMBL29628861 1.00 MAPT (1.00) MAPTNPC1RAB9ACALM1PKM
SCHEMBL31238426 0.97 MAPT (0.94) MAPTNPC1RAB9ACALM1PKM
SCHEMBL31741263 0.90 MAPT (1.00) MAPTNPC1RAB9ACALM1PKM
SCHEMBL311405 0.90 MAPT (1.00) MAPTNPC1RAB9ACALM1PKM
SCHEMBL4277649 0.89 MAPT (1.00) MAPTNPC1RAB9ACALM1PKM
SCHEMBL31238485 0.87 MAPT (0.77) MAPTNPC1RAB9ACALM1PKM
SCHEMBL31238451 0.87 MAPT (0.77) MAPTNPC1RAB9ACALM1PKM
7-Hydroxyflavone SCHEMBL312148 0.87 CYP19A1 (1.00) MAPTNPC1RAB9ACALM1PKM
7-Hydroxyflavone SCHEMBL29678183 0.87 CYP19A1 (1.00) MAPTNPC1RAB9ACALM1PKM
7-Hydroxyflavone SCHEMBL10808394 0.86 CYP19A1 (0.97) MAPTNPC1RAB9ACALM1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
EP-4599048-A1 COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS Trailhead Biosystems Inc. (US) 2025-08-13 EP claimed
EP-4577639-A1 METHODS AND COMPOSITIONS FOR SMALL MOLECULE BASED PANCREATIC BETA CELL INDUCTION Trailhead Biosystems Inc. (US) 2025-07-02 EP claimed
EP-4569090-A2 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2025-06-18 EP claimed
US-20250163379-A1 METHOD FOR DIFFERENTIATING HEMATOPOIETIC STEM/PROGENITOR CELLS INTO NK CELLS HEMACELL BIOTECHNOLOGY INC. (CN) 2025-05-22 US claimed
CN-119654404-A Methods and compositions for producing oligodendrocyte progenitor cells 特雷尔赫德生物系统股份有限公司 2025-03-18 CN claimed
CN-119604622-A Transmembrane nucleic acid nanostructures triggering assembly UCL 商业有限公司 2025-03-11 CN claimed
US-20250052737-A1 TRIGGER-ASSEMBLED MEMBRANE-SPANNING NUCLEIC ACID NANOSTRUCTURES UCL BUSINESS LTD (GB) 2025-02-13 US claimed
EP-4486919-A1 TRIGGER-ASSEMBLED MEMBRANE-SPANNING NUCLEIC ACID NANOSTRUCTURES UCL Business Ltd (GB) 2025-01-08 EP claimed
CN-118986960-A Compound for inhibiting nutrient absorption of small intestine and application thereof 上海市内分泌代谢病研究所 2024-11-22 CN claimed
US-20080254519-A1 Process for Producing Picolinic Acid Compounds SHINDO KAZUTOSHI 2008-10-16 US claimed
US-20070160688-A1 Use of flavonoids to increase blood serum levels of dehydroepiandrosterone PROPRIETARY WELLNESS, LLC 2007-07-12 US claimed
EP-1726645-A1 PROCESS FOR PRODUCING PICOLINIC ACID COMPOUNDS MARINE BIOTECHNOLOGY INSTITUTE CO., LTD. (JP) 2006-11-29 EP claimed
WO-2006041523-A1 FLUORESCENT POLY(ALKYLENE TEREPHTHALATE) COMPOSITIONS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-04-20 WO claimed
US-20060041039-A1 Fluorescent poly(alkylene terephthalate) compositions E. I. DU PONT DE NEMOURS AND COMPANY 2006-02-23 US claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
EP-0081621-A1 Chromones PENNWALT CORPORATION (US) 1983-06-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070160688-A1 Use of flavonoids to increase blood serum levels of dehydroepiandrosterone SHBG, CYP17A1, HSD17B11 MAPT 3855/4885NPC1 406/4885RAB9A 3391/4885
US-20080254519-A1 Process for Producing Picolinic Acid Compounds HPD, PAH, DHPS MAPT 2655/4885NPC1 2034/4885RAB9A 4721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.