Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17008897 | 0.83 | MEN1 (0.44) | MAPTLMNAKMT2AMEN1KDM4E | |
| SCHEMBL31144882 | 0.79 | KDM4E (0.57) | MAPTLMNAKMT2AMEN1KDM4E | |
| SCHEMBL1912821 | 0.75 | MAPT (0.66) | MAPTLMNAKMT2AMEN1NPSR1 | |
| SCHEMBL31144985 | 0.75 | POLB (0.37) | MAPTLMNAKMT2AMEN1KDM4E | |
| SCHEMBL30632281 | 0.73 | KDM4E (0.56) | MAPTLMNAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL31144951 | 0.72 | LMNA (0.40) | LMNAKMT2AMEN1KDM4EPDE4A | |
| SCHEMBL31144864 | 0.71 | MEN1 (0.49) | MAPTKMT2AMEN1KDM4EADORA2A | |
| SCHEMBL31492953 | 0.67 | MEN1 (0.46) | MAPTKMT2AMEN1NPSR1PDE4A | |
| SCHEMBL19010741 | 0.67 | L3MBTL1 (0.39) | MAPTLMNASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL23657286 | 0.66 | MAPT (0.58) | MAPTLMNAKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175804-A1 | NUCLEAR TRANSPORT MODULATORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-08-29 | — | — | WO | disclosed |