Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940300 | 0.81 | SRD5A1 (0.34) | MAOBESR1ESR2CDK1CDK2 | |
| SCHEMBL31145023 | 0.74 | RAB9A (0.40) | RAB9A | |
| SCHEMBL31284722 | 0.73 | CES1 (0.38) | MAOBRAB9A | |
| SCHEMBL31145015 | 0.71 | MAOB (0.38) | MAOBRAB9AESR1ESR2CDK1 | |
| SCHEMBL30940294 | 0.67 | PIK3CA (0.37) | CDK2 | |
| SCHEMBL31284512 | 0.67 | MAPKAPK2 (0.33) | — | |
| SCHEMBL24912965 | 0.66 | ALDH1A1 (0.50) | MAOBRAB9AESR1ESR2CDK2 | |
| SCHEMBL30940312 | 0.65 | DHODH (0.34) | RAB9ACDK2 | |
| SCHEMBL30940290 | 0.65 | PIK3CA (0.39) | CDK2 | |
| SCHEMBL25185329 | 0.64 | MAOB (0.37) | MAOBESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791498-A | Tetracyclic compound, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-10-18 | — | — | CN | disclosed |