Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18398215 | 0.84 | DCTPP1 (0.42) | DCTPP1MERTKNPC1RAB9AAPLNR | |
| SCHEMBL31146874 | 0.81 | LMNA (0.42) | NPC1RAB9AAPLNRMAPTALDH1A1 | |
| SCHEMBL1457286 | 0.80 | NPC1 (0.45) | DCTPP1NPC1RAB9AAPLNRMAPT | |
| SCHEMBL3787500 | 0.78 | MERTK (0.59) | DCTPP1MERTKNPC1MAPTALDH1A1 | |
| SCHEMBL25381487 | 0.76 | LMNA (0.47) | DCTPP1NPC1RAB9AAPLNRMAPT | |
| SCHEMBL29388790 | 0.76 | PIK3CA (0.40) | DCTPP1NPC1RAB9AAPLNRMAPT | |
| SCHEMBL20324230 | 0.76 | PIK3CA (0.40) | DCTPP1NPC1RAB9AAPLNRMAPT | |
| SCHEMBL29809131 | 0.76 | TP53 (0.39) | DCTPP1MERTKNPC1RAB9AAPLNR | |
| SCHEMBL29756227 | 0.75 | LMNA (0.39) | DCTPP1MERTKNPC1RAB9AAPLNR | |
| SCHEMBL27213608 | 0.75 | LMNA (0.39) | DCTPP1MERTKNPC1RAB9AAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731038-A | Nitrogen-containing heterocyclic compound, and preparation method and application thereof | 苏州亚盛药业有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-1924581-A1 | HYDROXY SUBSTITUTED 1H-IMIDAZOPYRIDINES AND METHODS | Pfizer, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028129-A1 | HYDROXY SUBSTITUTED 1H-IMIDAZOPYRIDINES AND METHODS | PFIZER INC. (US) | 2007-03-08 | — | — | WO | disclosed |