Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995590 | 0.73 | CHRNA7 (0.34) | TSHRHSD17B10L3MBTL1NPC1RAB9A | |
| SCHEMBL31146887 | 0.73 | TAAR1 (0.32) | — | |
| SCHEMBL31146868 | 0.67 | PTGS2 (0.40) | TSHRHSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31146889 | 0.66 | NPC1 (0.40) | TSHRL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31709528 | 0.64 | CYP3A4 (0.44) | HSD17B10L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1742802 | 0.64 | CYP3A4 (0.44) | HSD17B10L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31146867 | 0.64 | CYP3A4 (0.38) | SMN1; SMN2ALDH1A1HPGDCYP3A4POLB | |
| SCHEMBL31146882 | 0.64 | DAO (0.35) | NPC1RAB9AKMT2A | |
| SCHEMBL14518799 | 0.62 | NPC1 (0.46) | GABRA1GABRB2L3MBTL1NPC1RAB9A | |
| SCHEMBL29009667 | 0.61 | HPGD (0.56) | GABRA1GABRB2TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680606-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | AtmosR (FR) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024194175-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | ATMOSR (FR) | 2024-09-26 | — | — | WO | disclosed |