Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821774 | 0.72 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL20788996 | 0.70 | ULK1 (0.52) | KDM4EALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL31709528 | 0.70 | CYP3A4 (0.44) | ALDH1A1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL1742802 | 0.70 | CYP3A4 (0.44) | ALDH1A1NPC1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL20789009 | 0.67 | NPC1 (0.55) | KDM4EALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL23873646 | 0.66 | NPC1 (0.57) | KDM4EALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL31146894 | 0.64 | CYP1A2 (0.40) | ALDH1A1HPGDNPC1SMN1; SMN2RAB9A | |
| SCHEMBL24463551 | 0.64 | KDM4E (0.41) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL31146889 | 0.64 | NPC1 (0.40) | KDM4EALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL1034359 | 0.64 | MAPK10 (0.50) | KDM4EALDH1A1HPGDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680606-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | AtmosR (FR) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024194175-A1 | ADENINE DERIVATIVES AS HSP90 INHIBITORS | ATMOSR (FR) | 2024-09-26 | — | — | WO | disclosed |