Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165225 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2PDE3BPDE3AHPGD | |
| SCHEMBL8197895 | 0.90 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2PDE3BPDE3AHPGD | |
| SCHEMBL30208243 | 0.90 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2PDE3BPDE3AHPGD | |
| SCHEMBL13343548 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGDKDM4EGABRA1 | |
| SCHEMBL160847 | 0.85 | GABRA1 (0.46) | ALDH1A1HPGDKDM4EGABRA1GABRB1 | |
| SCHEMBL13343558 | 0.85 | TSHR (0.51) | ALDH1A1SMN1; SMN2HPGDKDM4EGABRA1 | |
| SCHEMBL13343406 | 0.85 | ALOX15 (0.51) | ALDH1A1SMN1; SMN2PDE3BPDE3AHPGD | |
| SCHEMBL166851 | 0.84 | MMP13 (0.58) | ALDH1A1HPGDKDM4EGAACYP1A2 | |
| SCHEMBL16792659 | 0.83 | SIRT2 (0.50) | ALDH1A1SMN1; SMN2PDE3BPDE3AHPGD | |
| SCHEMBL13343425 | 0.82 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HPGDKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698544-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220946-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |