Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119585 | 1.00 | GFER (0.39) | GFERTRPA1PORCNINSRALK | |
| SCHEMBL3113702 | 0.79 | GFER (0.41) | GFERCAPN1CES2ALDH1A1TACR1 | |
| SCHEMBL4234097 | 0.79 | GFER (0.41) | GFERCAPN1CES2ALDH1A1TACR1 | |
| SCHEMBL3113775 | 0.79 | GFER (0.37) | GFERCAPN1CES2ALDH1A1TACR1 | |
| SCHEMBL3113774 | 0.79 | GFER (0.37) | GFERCAPN1CES2ALDH1A1TACR1 | |
| SCHEMBL2793360 | 0.77 | GFER (0.41) | GFERCAPN1CES2TACR1MEN1 | |
| SCHEMBL2793358 | 0.77 | GFER (0.41) | GFERCAPN1CES2TACR1MEN1 | |
| SCHEMBL3121578 | 0.76 | MMP2 (0.36) | GFERCAPN1CES2ALDH1A1TACR1 | |
| SCHEMBL3112948 | 0.76 | GFER (0.35) | GFERCAPN1CES2ALDH1A1TACR1 | |
| SCHEMBL3121585 | 0.76 | MMP2 (0.36) | GFERCAPN1CES2ALDH1A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137396-A1 | Piperazine Compounds with a Herbicidal Action | BASF SE (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137396-A1 | Piperazine Compounds with a Herbicidal Action | DDT, CIP2A, PFAS | GFER 1334/4885TRPA1 757/4885PORCN 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.