Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739704 | 0.89 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL28512436 | 0.80 | PDE4A (0.43) | PDE4APDE4CPDE4DL3MBTL1METAP2 | |
| SCHEMBL5372354 | 0.79 | CYP1A2 (0.43) | KDM4EMEN1KMT2ACYP3A4GAA | |
| SCHEMBL4818198 | 0.77 | METAP2 (0.42) | KDM4EMEN1KMT2AALDH1A1PDE4A | |
| SCHEMBL249779 | 0.77 | METAP2 (0.64) | KDM4EMEN1KMT2APDE4APDE4C | |
| SCHEMBL2379509 | 0.76 | SLC40A1 (0.40) | KDM4EPDE4APDE4CPDE4DCYP3A4 | |
| SCHEMBL737308 | 0.76 | SLC40A1 (0.48) | KDM4EKMT2AALDH1A1TDP1PDE4A | |
| SCHEMBL15125330 | 0.76 | DRD2 (0.35) | MEN1KMT2APDE4APDE4CPDE4D | |
| SCHEMBL29751503 | 0.75 | AR (0.40) | KDM4EPDE4APDE4CPDE4DL3MBTL1 | |
| SCHEMBL27711752 | 0.75 | SLC40A1 (0.47) | KDM4EMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024206284-A2 | THERAPEUTIC COMPOUNDS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-10-03 | — | — | WO | disclosed |