Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31159014 | 0.85 | GPR119 (0.45) | GPR119 | |
| SCHEMBL30726307 | 0.84 | RORC (0.48) | JAK2JAK1 | |
| SCHEMBL31159120 | 0.82 | MAPT (0.47) | GPR119 | |
| SCHEMBL31158818 | 0.81 | MAPT (0.47) | GPR119 | |
| SCHEMBL31159182 | 0.81 | GPR119 (0.48) | GPR119EGLN2JAK2JAK1RET | |
| SCHEMBL15544104 | 0.79 | GPR119 (0.49) | GPR119EGLN2JAK2JAK1 | |
| SCHEMBL31159047 | 0.78 | MMP13 (0.40) | GPR119EGLN2JAK2JAK1 | |
| SCHEMBL31420555 | 0.78 | GPR119 (0.51) | GPR119EGLN2AR | |
| SCHEMBL15601478 | 0.77 | GPR119 (0.50) | GPR119EGLN2JAK2JAK1AR | |
| SCHEMBL2357533 | 0.77 | NAMPT (0.57) | GPR119EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |