Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30726307 | 0.88 | RORC (0.48) | PTPN2PTPN1PTPN6NAMPTSMN1; SMN2 | |
| SCHEMBL31159120 | 0.87 | MAPT (0.47) | GPR119KMT2AMMP13MEN1SMN1; SMN2 | |
| SCHEMBL31158818 | 0.86 | MAPT (0.47) | GPR119MMP13RORC | |
| SCHEMBL31158840 | 0.85 | GPR119 (0.49) | GPR119 | |
| SCHEMBL31159047 | 0.82 | MMP13 (0.40) | GPR119KMT2AMMP13PTPN2PTPN1 | |
| SCHEMBL31159143 | 0.79 | HDAC2 (0.51) | KMT2AMMP13MEN1SCD5RORC | |
| SCHEMBL31158870 | 0.78 | KIF11 (0.41) | GPR119RORC | |
| SCHEMBL31639625 | 0.78 | NR1H2 (0.39) | GPR119KMT2AMEN1NR1H2 | |
| SCHEMBL25603154 | 0.78 | NR1H2 (0.39) | GPR119NR1H2GRM5GRM1 | |
| SCHEMBL21767846 | 0.76 | NAMPT (0.52) | GPR119KMT2AMMP13PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |