Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22743005 | 0.84 | HDAC8 (0.55) | HDAC8HDAC4HDAC5HDAC7HDAC6 | |
| SCHEMBL7326935 | 0.78 | DNMT1 (0.51) | HDAC8HDAC4HDAC5SMARCA2PTAFR | |
| SCHEMBL7330633 | 0.73 | HDAC8 (0.53) | HDAC8HDAC4HDAC5HDAC6SMARCA2 | |
| SCHEMBL12985464 | 0.71 | HDAC8 (0.42) | HDAC8HDAC4HDAC5HDAC7HDAC6 | |
| SCHEMBL7338632 | 0.71 | HDAC8 (0.53) | HDAC8HDAC4HDAC5HDAC7HDAC6 | |
| SCHEMBL7336717 | 0.70 | HDAC8 (0.51) | HDAC8HDAC4HDAC5HDAC7HDAC6 | |
| SCHEMBL87137 | 0.69 | HDAC8 (0.40) | HDAC8HDAC4HDAC5HDAC7HDAC6 | |
| SCHEMBL7335787 | 0.67 | HDAC8 (0.56) | HDAC8HDAC4HDAC5HDAC7HDAC6 | |
| SCHEMBL18824790 | 0.67 | HDAC8 (0.71) | HDAC8HDAC4HDAC5HDAC7HDAC6 | |
| SCHEMBL19931148 | 0.66 | S100A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240086-A1 | COMPOUND FOR REGULATING AND CONTROLLING 15-PGDH ACTIVITY AND PREPARATION METHOD THEREFOR | 成都倍特药业股份有限公司 | 2024-11-28 | — | — | WO | disclosed |