Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664092 | 0.82 | HSP90AB1 (0.47) | L3MBTL1ATMPDE10ACYP1A2CYP2A6 | |
| SCHEMBL3121339 | 0.81 | HTR2B (0.50) | L3MBTL1ATMPDE10ACYP1A2CYP2A6 | |
| SCHEMBL23715914 | 0.79 | CYP1A2 (0.48) | L3MBTL1ATMPDE10ACYP1A2CYP2A6 | |
| SCHEMBL3116975 | 0.76 | NPC1 (0.55) | L3MBTL1ATMPDE10ACYP1A2CYP2A6 | |
| SCHEMBL3129580 | 0.76 | SLC6A2 (0.44) | L3MBTL1ATMPDE10ATDP1NPC1 | |
| SCHEMBL17664090 | 0.73 | NPC1 (0.40) | L3MBTL1ATMPDE10ACYP1A2CYP2A6 | |
| SCHEMBL2908675 | 0.70 | L3MBTL1 (0.51) | L3MBTL1ATMPDE10ACYP1A2CYP2A6 | |
| SCHEMBL3119876 | 0.70 | CYP1A2 (0.46) | L3MBTL1ATMPDE10ACYP1A2CYP2A6 | |
| SCHEMBL3121450 | 0.70 | HTR2C (0.42) | L3MBTL1ATMPDE10AHTR2BKDM4E | |
| SCHEMBL21363719 | 0.70 | CYP2A6 (0.50) | L3MBTL1ATMPDE10ACYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296967-A1 | QUINOLINYL AND BENZOTHIAZOLYL PPAR-GAMMA MODULATORS | Tularik Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2002000633-A1 | QUINOLINYL AND BENZOTHIAZOLYL PPAR-GAMMA MODULATORS | TULARIK INC. (US) | 2002-01-03 | — | — | WO | disclosed |