Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136815 | 0.82 | FAAH (0.36) | USP2SMN1; SMN2POLBHTTATM | |
| SCHEMBL17276537 | 0.81 | POLB (0.49) | USP2SMN1; SMN2POLBGPR119 | |
| SCHEMBL28323959 | 0.79 | CYP1A2 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL27388627 | 0.78 | USP2 (0.62) | USP2SMN1; SMN2POLBHTTATM | |
| SCHEMBL17276687 | 0.77 | POLB (0.46) | USP2SMN1; SMN2POLBGPR119MEN1 | |
| SCHEMBL31169844 | 0.76 | USP2 (0.49) | USP2SMN1; SMN2POLBHTTATM | |
| SCHEMBL31170642 | 0.76 | GPR119 (0.44) | USP2SMN1; SMN2POLBHTTATM | |
| SCHEMBL18294 | 0.76 | USP2 (0.69) | USP2SMN1; SMN2POLBHTTATM | |
| SCHEMBL698803 | 0.76 | USP2 (0.69) | USP2SMN1; SMN2POLBHTTATM | |
| SCHEMBL2262506 | 0.76 | ALDH1A1 (0.52) | USP2SMN1; SMN2POLBHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238633-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-11-21 | — | — | WO | disclosed |