Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705062 | 0.83 | APEX1 (0.63) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7458037 | 0.81 | CA2 (0.57) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9050843 | 0.80 | MAPT (1.00) | ALDH1A1MAPTGAAAPEX1SMN1; SMN2 | |
| SCHEMBL9850820 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTAPEX1SMN1; SMN2TSHR | |
| SCHEMBL15801080 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTKDM4EGAAAPEX1 | |
| SCHEMBL9850742 | 0.79 | MEN1 (0.62) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL11326715 | 0.79 | APEX1 (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8324749 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL7764834 | 0.78 | MEN1 (0.50) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL11303910 | 0.78 | MAPT (0.52) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008153289-A2 | PROCESS FOR PREPARING BEPOTASTINE AND INTERMEDIATES USED THEREIN | HANMI PHARM. CO., LTD. (KR) | 2008-12-18 | — | — | WO | disclosed |
| US-5514589-A | ACYLATION OF COMPOUND IN THE PRESENCE OF LIPASE IMMOBILIZED ON SUPPORT OF SACCHAROSE | ORION-YHTYMA OY FERMION (FI) | 1996-05-07 | — | — | US | disclosed |
| EP-0617130-A2 | Method for the resolution of racemic mixtures | ORION-YHTYMÄ OY FERMION (FI) | 1994-09-28 | — | — | EP | disclosed |