Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123591 | 0.92 | ABL1 (0.37) | ALDH1A1KDM4EMEN1LMNATTR | |
| SCHEMBL3108653 | 0.89 | CYP3A4 (0.38) | ALDH1A1MEN1TTRTP53CYP3A4 | |
| SCHEMBL3116230 | 0.85 | CALM1 (0.38) | CYP19A1 | |
| SCHEMBL3113566 | 0.84 | BACE1 (0.40) | ALDH1A1KDM4EMEN1LMNATTR | |
| SCHEMBL3118616 | 0.83 | ALOX15 (0.35) | ALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL15759397 | 0.82 | CYP4F2 (0.44) | TP53MAPT | |
| SCHEMBL11144108 | 0.81 | LMNA (0.44) | ALDH1A1KDM4EMEN1LMNATTR | |
| SCHEMBL17188986 | 0.80 | LMNA (0.53) | ALDH1A1KDM4EMEN1LMNATTR | |
| SCHEMBL15759390 | 0.80 | MAOB (0.35) | — | |
| SCHEMBL10725365 | 0.73 | LMNA (0.60) | ALDH1A1KDM4EMEN1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732645-B2 | Aromatic vinyl ether compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-2161248-A1 | Aromatic vinyl ether compounds | Daicel Chemical Industries, Ltd. (JP) | 2010-03-10 | — | — | EP | disclosed |
| US-7518021-B2 | Aromatic vinyl ether compounds | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-04-14 | — | — | US | disclosed |
| US-20090088592-A1 | AROMATIC VINYL ETHER COMPOUNDS | IWAHAMA TAKAHIRO | 2009-04-02 | — | — | US | disclosed |
| US-20040181098-A1 | Aromatic vinyl ether compounds | EMORY UNIVERSITY | 2004-09-16 | — | — | US | disclosed |
| EP-1413568-A2 | Aromatic vinyl ether compounds | Daicel Chemical Industries, Ltd. (JP) | 2004-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181098-A1 | Aromatic vinyl ether compounds | SUV39H2, SUV39H1, RAVER1 | ALDH1A1 282/4885KDM4E 87/4885MEN1 4117/4885 |
| US-20090088592-A1 | AROMATIC VINYL ETHER COMPOUNDS | SUV39H2, SUV39H1, RAVER1 | ALDH1A1 494/4885KDM4E 76/4885MEN1 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.