SCHEMBL3108653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3113566	0.95	BACE1 (0.40)	CYP3A4CALM1MEN1KMT2AGABRA1
	SCHEMBL3117282	0.89	ALDH1A1 (0.35)	CYP3A4MEN1KMT2AMAPTTDP1
	SCHEMBL3123591	0.82	ABL1 (0.37)	CYP3A4MEN1KMT2AMAPTBACE1
	SCHEMBL3118616	0.79	ALOX15 (0.35)	CYP3A4TDP1ALDH1A1MAPK1HPGD
	SCHEMBL19465393	0.78	CYP3A4 (0.66)	CYP3A4MEN1KMT2AGABRA1GABRB2
	SCHEMBL12830655	0.78	PTGS2 (0.65)	CYP3A4MEN1KMT2AMAPTTDP1
	SCHEMBL12830069	0.76	KDM4E (0.66)	CYP3A4MEN1KMT2AMAPTCA5A
	SCHEMBL3116230	0.76	CALM1 (0.38)	CALM1
	SCHEMBL14351002	0.75	CYP3A4 (0.63)	CYP3A4MEN1KMT2AMAPTBACE1
	SCHEMBL28080298	0.75	ESR2 (0.48)	CYP3A4CALM1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.