Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 19/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | HTR1E | P28566 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173223 | 0.81 | TMEM97 (0.61) | TMEM97SIGMAR1ESR2HRH2HTR2C | |
| SCHEMBL31173276 | 0.80 | TMEM97 (0.60) | TMEM97SIGMAR1ESR2HRH2HTR2C | |
| SCHEMBL12983493 | 0.80 | OPRM1 (0.52) | — | |
| SCHEMBL6161497 | 0.80 | TSHR (0.51) | SLC6A4ADRA1A | |
| SCHEMBL31173476 | 0.79 | TMEM97 (0.59) | TMEM97SIGMAR1ESR2HRH2HTR2C | |
| SCHEMBL31173345 | 0.78 | TMEM97 (0.58) | TMEM97SIGMAR1ESR2HRH2HTR2C | |
| SCHEMBL30645349 | 0.78 | TMEM97 (0.58) | TMEM97SIGMAR1ESR2HRH2HTR2C | |
| SCHEMBL27191477 | 0.78 | TMEM97 (0.58) | TMEM97SIGMAR1ESR2HRH2HTR2C | |
| SCHEMBL31173398 | 0.77 | TMEM97 (0.60) | TMEM97SIGMAR1ESR2HRH2HTR2C | |
| SCHEMBL31173293 | 0.77 | TMEM97 (0.57) | TMEM97SIGMAR1ESR2HRH2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4692057-A1 | NOVEL B0AT1 INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20260001849-A1 | NOVEL B0AT1 INHIBITOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2026-01-01 | — | — | US | disclosed |
| WO-2024210198-A1 | NOVEL B0AT1 INHIBITOR | 田辺三菱製薬株式会社 | 2024-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001849-A1 | NOVEL B0AT1 INHIBITOR | BCAT1, BCAT2, BHMT | TMEM97 1010/4885SIGMAR1 1486/4885ESR2 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.