Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312297 | 0.90 | NLRP3 (0.42) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL313026 | 0.90 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL312382 | 0.89 | CYP1A2 (0.39) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL311043 | 0.88 | CYP1A2 (0.38) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL312017 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL311889 | 0.85 | CYP1A2 (0.40) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL10215441 | 0.85 | KDM4E (0.45) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL312363 | 0.84 | CYP1A2 (0.37) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL311236 | 0.84 | PLA2G7 (0.45) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL312303 | 0.83 | TUBB4A (0.40) | ALDH1A1HSD17B10KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |