⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914508 | 0.86 | — | — | |
| SCHEMBL8220411 | 0.84 | LPAR3 (0.47) | — | |
| SCHEMBL3332214 | 0.82 | LPAR3 (0.50) | — | |
| SCHEMBL16242411 | 0.82 | LPAR3 (0.50) | — | |
| SCHEMBL8220810 | 0.82 | LPAR3 (0.50) | — | |
| SCHEMBL1416536 | 0.82 | LPAR3 (0.50) | — | |
| SCHEMBL47886 | 0.81 | CA2 (0.42) | — | |
| SCHEMBL370793 | 0.79 | CA2 (0.39) | — | |
| SCHEMBL28080557 | 0.79 | LMNA (0.46) | — | |
| SCHEMBL28919286 | 0.79 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108942-B1 | CEPHALOSPORIN DERIVATIVES, METHODS OF PRODUCTION THEREOF AND PROPHYLACTIC AND THERAPEUTIC AGENTS FOR BACTERIAL INFECTION | KYOTO PHARMA IND (JP) | 1988-03-02 | — | — | EP | claimed |
| EP-0163240-A2 | Dihydroimidazo[1,2-a]pyrimidine derivatives, methods of preparing said compounds and pharmaceutical compositions constaining said compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-12-04 | — | — | EP | claimed |
| CN-116987080-A | Macrocyclic compounds with heterocyclic P2' groups as factor XIA inhibitors | 百时美施贵宝公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-106132962-B | Macrocyclic compounds having an aromatic P2' group as factor XIA inhibitors | 百时美施贵宝公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-107428942-A | Curable silicone composition | 莫门蒂夫性能材料股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| US-9783512-B2 | Bicyclic methylene aziridines and reactions thereof | WISCONSIN ALUMI RESEARCH FOUNDATION (US) | 2017-10-10 | — | — | US | disclosed |
| CN-106132962-A | Macrocyclic compounds having an aromatic P2' group as factor XIA inhibitors | 百时美施贵宝公司 | 2016-11-16 | — | — | CN | disclosed |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | MEIJI SEIKA KAISHA (JP) | 2016-06-02 | — | — | US | disclosed |
| US-9260375-B2 | Metallo-β-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| EP-2755949-B1 | FUNGICIDAL 4-SUBSTITUTED-3-{PHENYL[(HETEROCYCLYLMETHOXY)IMINO]METHYL}-1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES | BAYER IP GMBH (DE) | 2015-10-21 | — | — | EP | disclosed |
| US-9090600-B2 | Fungicidal 4-substituted-3-{phenyl[(heterocyclylmethoxy)imino]methyl}-1,2,4-oxadizol-5(4H)-one derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| EP-1941873-A1 | METALLO-BETA-LACTAMASE INHIBITOR | MEIJI SEIKA KAISHA LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20080090825-A1 | Metallo-beta-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| US-6444656-B1 | (5R)-(2-AMINO-6-HYDROXY-PURIN-9-YLMETHYL)-(4R)-AZIDO-TETRAHYDR O-FURAN-(2S)- PHOSPHONATE; PARTICULARLY AGAINST HIV AND/OR HBV INFECTIONS | BIOCHEM PHARMA, INC. (CA) | 2002-09-03 | — | — | US | disclosed |
| US-20020061896-A1 | Imidazopyrimidine nucleoside analogues with anti-HIV activity | BIOCHEM PHARMA, INC. (CA) | 2002-05-23 | — | — | US | disclosed |
| WO-2001049700-A1 | IMIDAZOPYRIMIDINE NUCLEOSIDE ANALOGUES WITH ANTI-HIV ACTIVITY | BIOCHEM PHARMA INC. (CA) | 2001-07-12 | — | — | WO | disclosed |
| EP-0108942-B1 | CEPHALOSPORIN DERIVATIVES, METHODS OF PRODUCTION THEREOF AND PROPHYLACTIC AND THERAPEUTIC AGENTS FOR BACTERIAL INFECTION | KYOTO PHARMA IND (JP) | 1988-03-02 | — | — | EP | disclosed |
| EP-0163240-A3 | Dihydroimidazo[1,2-a]pyrimidine derivatives, methods of preparing said compounds and pharmaceutical compositions constaining said compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-04-22 | — | — | EP | disclosed |
| EP-0163240-A2 | Dihydroimidazo[1,2-a]pyrimidine derivatives, methods of preparing said compounds and pharmaceutical compositions constaining said compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-12-04 | — | — | EP | disclosed |
| EP-0163240-A2 | Dihydroimidazo[1,2-a]pyrimidine derivatives, methods of preparing said compounds and pharmaceutical compositions constaining said compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-12-04 | — | — | EP | disclosed |