SCHEMBL370793

SCHEMBL370793

C=CCCOC(=O)C(=C)N

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 2/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
THRB P10828 1/20 0.31
TSHR P16473 7/20 0.31
ALDH1A1 P00352 6/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FGFR4 P22455 1/20 0.31
LMNA P02545 1/20 0.31
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31
ABCC4 O15439 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL7101033 0.82 THRB (0.48) CA2CA9KDM4EMAPTTHRB
SCHEMBL5822460 0.80 ABCC4 (0.35) CA2CA9KDM4EMAPTTHRB
SCHEMBL311772 0.79
SCHEMBL809330 0.78 THRB (0.53) CA2CA9KDM4EMAPTTHRB
SCHEMBL432465 0.77
SCHEMBL20849748 0.77 TSHR (0.59) MAPTCACNA1BAPBA1THRBTSHR
SCHEMBL47886 0.76 CA2 (0.42) CA2CA9KDM4EMAPTTSHR
Bicarbonate SCHEMBL29257315 0.75 THRB (0.50) CA2CA9MAPTTHRBTSHR
SCHEMBL14947426 0.75
SCHEMBL728980 0.74 ALDH1A1 (0.35) CA2CA9MAPTTHRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100000946-A1 PRODUCTION OF A FERMENTATION PRODUCT HUGHES JONATHAN 2010-01-07 US claimed
EP-0474452-B1 Thermal transfer dye image receiving sheet NEW OJI PAPER CO LTD (JP) 1995-07-12 EP claimed
US-5316999-A Heat exchanging and receivers with vinyl chloride and vinyl propionate copolymers OJI PAPER CO., LTD. (JP) 1994-05-31 US claimed
EP-0474452-A2 Thermal transfer dye image receiving sheet NEW OJI PAPER CO., LTD. (JP) 1992-03-11 EP claimed
US-8097127-B2 Siliceous composition and its use in papermaking BASF SE (DE) 2012-01-17 US disclosed
US-8067193-B2 Production of a fermentation product CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2011-11-29 US disclosed
US-20110240240-A1 AQUEOUS POLYSILICATE COMPOSITION, ITS PREPARATION AND ITS USE IN PAPERMAKING BASF SE (DE) 2011-10-06 US disclosed
EP-2370358-A2 AQUEOUS POLYSILICATE COMPOSITION, ITS PREPARATION AND ITS USE IN PAPERMAKING BASF SE (DE) 2011-10-05 EP disclosed
WO-2010060805-A2 AQUEOUS POLYSILICATE COMPOSITION, ITS PREPARATION AND ITS USE IN PAPERMAKING BASF SE (DE) 2010-06-03 WO disclosed
US-20090236065-A1 SILICEOUS COMPOSITION AND ITS USE IN PAPERMAKING BASF SE (DE) 2009-09-24 US disclosed
EP-2069573-A2 SILICEOUS COMPOSITION AND ITS USE IN PAPERMAKING Ciba Holding Inc. (CH) 2009-06-17 EP disclosed
US-7470346-B2 Aqueous compositions and their use in the manufacture of paper and paperboard CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2008-12-30 US disclosed
WO-1996031653-A1 TISSUE PAPER CONTAINING A FINE PARTICULATE FILLER THE PROCTER & GAMBLE COMPANY (US) 1996-10-10 WO disclosed
EP-0335576-B1 PULP DEWATERING PROCESS Ciba Specialty Chemicals Water Treatments Limited (GB) 1993-05-12 EP disclosed
US-4969976-A CATIONIC POLYMER, SHEARING ALLIED COLLOIDS LTD. (GB) 1990-11-13 US disclosed
EP-0365279-A2 Agricultural compositions Ciba Specialty Chemicals Water Treatments Limited (GB) 1990-04-25 EP disclosed
EP-0087859-B1 THERMAL ENERGY STORAGE COMPOSITIONS Ciba Specialty Chemicals Water Treatments Limited (GB) 1986-04-30 EP disclosed
US-4537695-A Thermal energy storage compositions HAWE MALCOLM (GB) 1985-08-27 US disclosed
US-4470917-A LIQUID AND COLID PHASE OF DIFFERENT DENSITIES IN POLYMERIC MATRIX ALLIED COLLOIDS LIMITED (GB) 1984-09-11 US disclosed
EP-0087859-A1 Thermal energy storage compositions Ciba Specialty Chemicals Water Treatments Limited (GB) 1983-09-07 EP disclosed